UniversitÓ degli Studi di Torino


 THE SITES

The Institute for Cancer Research and Treatment (I.R.C.C) is  a comprehensive Centre for research and cancer treatment with 3,000 m2 state-of-the-art research facilities hosting a staff of about 70 scientists affiliated to the University of Torino. The group leaders are well known scientists in their field, namely Paolo Comoglio, Federico Bussolino, Luigi Naldini, Federico Caligaris Capio, Massimo Aglietta e Flavia di Renzo.
The Division of Molecular Oncology  is devoted to the study of genes encoding growth factors and growth factor receptors. In particular it is interested in the MET oncogene family, the plexin gene family mediates cell repelling cues and the cell biology of invasive growth.
The Division of Molecular Angiogenesis focuses on understanding the molecular mechanisms of blood vessel formation. Cooperation between Growth factor and matrix protein signal transduction pathways in endothelial cells seems to be of central importance in this process. Furthermore a recent effort is done to study the role of axon guidance molecules (semaphorins) and proteins involved in neuron-neuron interactions (neurexins) in the direction of the nascent vessels and in the establishment of vascular boundaries. 
The research of the Laboratory of Gene Transfer and  Therapy focuses on the novel gene transfer technology: hybrid lentiviral vectors. The Research  Programme of the Laboratory is centred  on the  improvement of the available gene transfer tools to  meet these challenges: in vivo gene transfer, improved transduction efficiency, targeting and exogenous regulation of transgene expression. 
The Laboratory of Tumor Immunology is devoted to the cellular and molecular studies of diseases involving B Lymphocytes (Neoplasias, Immunodeficiency). Basic and clinical studies aim at understanding the mechanisms leading to the neoplastic transformation of B Lymphocytes. 
The Division of Clinical Oncology is devoted to the ex vivo expansion of hematopoietic transplantable cells and to the study of the characteristics and the ontogeny of the hematopoietic stem cells. 
The laboratory of Cancer Genetics  is devoted to the identification of genes responsible for cancer predisposition.
 

The Department of Theoretical Physics of  Torino University has a long established tradition in the fields of

  1. Phenomenology of Elementary Particles and Collider Physics
  2. Lattice Gauge Theories, Statistical Mechanics, integrable models
  3. Astroparticle physics and phenomenology
  4. String Theory, supergravity and supersymmetry
  5. Theoretical Nuclear Physics.
In particular the Department of Theoretical Physics of Torino University has a long standing tradition in Mathematical Physics associated with the fields of General Relativity, String Theory and supergravity. This tradition was established in the 60.s   by  Tullio Regge and Sergio Fubini and was continued in the 70.s and 80.s  by  present members of the Department, in particular by Ferdinando Gliozzi, Stefano Sciuto, Alessandro D'Adda, Riccardo D'Auria, Pietro Fré and Leonardo Castellani. The tradition in the other branches and in particular in Statistical Physics  which is mostly relevant, together with mathematical physics for this project is equally strong due to the well known school of  Ferdinando Gliozzi and Michele Caselle.

The Department of Clinical and Biological Sciences of  Torino University is a University Research Center where clinical and molecular research are strictly connected. A Unit of Genomics and Bioinformatics has been set up under the direction of Prof. Raffaele A. Calogero. The Unit is involved in the development of methods for the analysis and data mining of microarrays data (www.bioinformatica.unito.it). Furthermore a Proteomics  facility was recently set up under the direction of Prof. S. Bozzaro and R.A. Calogero. 

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