Institute for Cancer Research and Treatment (I.R.C.C)
is a comprehensive Centre for research and cancer treatment with
3,000 m2 state-of-the-art research facilities hosting a staff of about
70 scientists affiliated to the University of Torino. The group leaders
are well known scientists in their field, namely Paolo Comoglio, Federico
Bussolino, Luigi Naldini, Federico Caligaris Capio, Massimo Aglietta e
Flavia di Renzo.
The Division of Molecular Oncology
is devoted to the study of genes encoding growth factors and growth factor
receptors. In particular it is interested in the MET oncogene family, the
plexin gene family mediates cell repelling cues and the cell biology of
The Division of Molecular Angiogenesis
on understanding the molecular mechanisms of blood vessel formation. Cooperation
between Growth factor and matrix protein signal transduction pathways in
endothelial cells seems to be of central importance in this process. Furthermore
a recent effort is done to study the role of axon guidance molecules (semaphorins)
and proteins involved in neuron-neuron interactions (neurexins) in the
direction of the nascent vessels and in the establishment of vascular boundaries.
The research of the Laboratory
of Gene Transfer and Therapy focuses
on the novel gene transfer technology: hybrid lentiviral vectors. The Research
Programme of the Laboratory is centred on the improvement of
the available gene transfer tools to meet these challenges: in vivo
gene transfer, improved transduction efficiency, targeting and exogenous
regulation of transgene expression.
The Laboratory of Tumor Immunology
is devoted to the cellular and molecular studies of diseases involving
B Lymphocytes (Neoplasias, Immunodeficiency). Basic and clinical studies
aim at understanding the mechanisms leading to the neoplastic transformation
of B Lymphocytes.
The Division of Clinical Oncology
devoted to the ex vivo expansion of hematopoietic transplantable cells
and to the study of the characteristics and the ontogeny of the hematopoietic
The laboratory of Cancer Genetics
is devoted to the identification of genes responsible for cancer predisposition.
Department of Theoretical Physics of
Torino University has a long established tradition in the fields of
In particular the Department of Theoretical
Physics of Torino University has a long standing tradition in Mathematical
Physics associated with the fields of General Relativity, String Theory
and supergravity. This tradition was established in the 60.s
by Tullio Regge and Sergio Fubini and was continued in the 70.s and
80.s by present members of the Department, in particular by
Ferdinando Gliozzi, Stefano Sciuto, Alessandro D'Adda, Riccardo D'Auria,
Pietro Fré and Leonardo Castellani. The tradition in the other branches
and in particular in Statistical Physics which is mostly relevant,
together with mathematical physics for this project is equally strong due
to the well known school of Ferdinando Gliozzi and Michele Caselle.
Phenomenology of Elementary Particles
and Collider Physics
Lattice Gauge Theories, Statistical
Mechanics, integrable models
Astroparticle physics and phenomenology
String Theory, supergravity and supersymmetry
Theoretical Nuclear Physics.
Department of Clinical and Biological Sciences of
Torino University is a University Research Center where clinical and molecular
research are strictly connected. A Unit of Genomics and Bioinformatics
has been set up under the direction of Prof. Raffaele
A. Calogero. The Unit is involved in the development of methods for
the analysis and data mining of microarrays data (www.bioinformatica.unito.it).
Furthermore a Proteomics facility was recently set up under the direction
of Prof. S. Bozzaro and R.A. Calogero.